During high-frequency neuronal activity, increases in the extracellular potassium (K+) concentration may be observed around axons. The excess extracellular K+ is generally removed by glial cells via a process called K+ buffering. Which of the following processes may play a role in K+ buffering?

Physiology Test Question

During high-frequency neuronal activity, increases in the extracellular potassium (K⁺) concentration may be observed around axons. The excess extracellular K⁺ is generally removed by glial cells via a process called K⁺ buffering. Which of the following processes may play a role in K⁺ buffering?

	(A) Glial uptake of K⁺ via the Na⁺/K⁺/ATPase
	(B) Entry of K⁺ into glial cells via inwardly rectifying K⁺ channels (Kir)
	(C) Entry of K⁺ into glial cells via voltage-gated K⁺ channels (Kv)
	(D) Entry of K⁺ into glial cells via non-selective cation channels
	(E) Glial uptake of K⁺ via the Na⁺/K⁺/2Cl⁻ cotransporter (NKCC)

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