The figure below shows the reaction velocity catalyzed by an enzyme as a function of the enzyme substrate concentration. Such a relationship is typically referred to as a dose-response relationship. Based on the data shown, what is the Km (Michaelis constant) of this enzyme for its substrate? Note that the reaction velocity is normalized to the maximum velocity (Vmax). Therefore, in the plot shown, Vmax = 100%.

Physiology Test Question

The figure below shows the reaction velocity catalyzed by an enzyme as a function of the enzyme substrate concentration. Such a relationship is typically referred to as a dose-response relationship. Based on the data shown, what is the K_m (Michaelis constant) of this enzyme for its substrate? Note that the reaction velocity is normalized to the maximum velocity (V_max). Therefore, in the plot shown, V_max = 100%.

	(A) 2.5 nM
	(B) 5.0 nM
	(C) 10.0 nM
	(D) 20.0 nM
	(E) 25.0 nM

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