Before iodide can be incorporated into the thyroid hormones, it must leave the thyroid follicular cells through the apical membrane to enter colloid in the lumen of thyroid follicles. Iodide transport across the apical membrane of follicular cells is accomplished by:

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Physiology Test Question

Before iodide can be incorporated into the thyroid hormones, it must leave the thyroid follicular cells through the apical membrane to enter colloid in the lumen of thyroid follicles. Iodide transport across the apical membrane of follicular cells is accomplished by:

	(A) simple diffusion of iodide through the apical membrane
	(B) the activity of the Na⁺/iodide symporter (NIS)
	(C) Cl⁻/I⁻ exchange
	(D) movement of iodide out of the cell and into the follicle lumen down its electrochemical gradient through an as yet unidentified iodide channel in the apical membrane
	(E) C and D are possible mechanisms

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Posted: Tuesday, January 20, 2015
Last updated: Tuesday, January 20, 2015