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Glossary of Physiology Terms -
Threshold

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Threshold

Definition:
The membrane voltage that must be reached in an excitable cell (e.g., neuron or muscle cell) during a depolarization in order to generate an action potential. At the threshold voltage, voltage-gated channels become activated. Threshold is approximately −50 to −40 mV in most excitable cells.

Related glossary terms/phrases:
Sub-threshold
Supra-threshold

See also:
Neuronal Action Potential - Introduction




Posted: Sunday, February 16, 2014
Last updated: Wednesday, March 12, 2025
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