Electrogenic
Definition:
An electrogenic transport process is one that leads to the translocation of net charge across the membrane. For example, ion channels such as Na
+, K
+, Ca
2+, and Cl
− channels are electrogenic.
The Na
+/K
+ ATPase is electrogenic because for every ATP molecule hydrolyzed, 3 Na
+ ions are transported out of the cell and 2 K
+ ions are transported into the cell (leading to the translocation of one net positive charge out of the cell).
Many
secondary active transporters are also electrogenic. For example, the Na
+/glucose cotransporter (found in the small intestine and kidney proximal tubules), transports 2 Na
+ ions and 1 glucose molecule into the cell across the plasma membrane (leading to the translocation of two net positive charges into the cell per transport cycle).
Posted: Saturday, February 1, 2014
Last updated: Wednesday, March 12, 2025