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Glossary of Physiology Terms -
Chloride

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Chloride

Abbreviation:
CI−

Definition:
The main anion (negatively charged ion) of the extracellular fluid.

Cloride (Cl−) plays an important role in several physiological processes such as the action potential of skeletal muscle cells, CO2 transport in blood (via Cl−/bicarbonate exchange across the plasma membrane of red blood cells), and many other processes.

The extracellular concentration of Cl− is about 110 mM. The intracellular concentration of Cl− is about 10 mM.




Posted: Wednesday, February 5, 2014
Last updated: Wednesday, March 12, 2025
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