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Glossary of Physiology Terms -
Channel inactivation

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Channel inactivation

Definition:
Refers to a conformational change of a channel protein by which the channel goes from the open state to the inactive state. The inactive state refers to a conformational state in which ions are not allowed to permeate the channel pore. Thus, with respect to ion permeability, the inactive state is similar to the close state of the channel. Ions cannot permeate the channel pore either in the closed or inactive state. However, the channel assumes very distinct and different conformations in the inactive state and closed state.

See also:
Neuronal Action Potential - Important Features of the Neuronal Action Potential




Posted: Saturday, March 1, 2014
Last updated: Wednesday, March 12, 2025
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