PhysiologyWeb Logo  Search
PhysiologyWeb Loading...

Glossary of Physiology Terms
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Search

There are 3 glossary search results for:   Voltage-gated sodium channels




Definition:
Neurotoxins are chemical molecules that have an adverse effect on neuron function and, thus, disrupt the normal function of the nervous system. Neurotoxins could be small molecules or peptides and can be derived from a variety of invertebrate and vertebrate animals, as well as plant species.

The following is a short list of some examples of neurotoxins:

α-Bungarotoxin: A peptide neurotoxin that inhibits the nicotinic acetylcholine receptor.

Chlorotoxin: A peptide neurotoxin that inhibits chloride channels.

α-Conotoxin: A peptide neurotoxin that inhibits the nicotinic acetylcholine receptor.

δ-Conotoxin: A peptide neurotoxin that inhibits voltage-gated sodium channels.

w-Conotoxin: A peptide neurotoxin that inhibits N-type voltage-gated calcium channels.

Picrotoxin: Inhibits GABAA receptor chloride channels.

Tetrodotoxin: Inhibitor of neuronal voltage-gated sodium channels.



Abbreviation:
TEA

Definition:
An inhibitor of voltage-gated potassium (K+) channels.

TEA is a quaternary ammonium cation (positively charged ion). It is also commonly used as a cation replacement for sodium (Na+) in physiological buffers used in ion replacement experiments.

See also:
Pharmacological Inhibition of Na+ and K+ Channels



Abbreviation:
TTX

Definition:
Inhibitor of fast voltage-gated sodium (Na+) channels of neurons and muscle cells. It is an extremely potent and toxic neurotoxin.

See also:
Pharmacological Inhibition of Na+ and K+ Channels

Other resources:
Tetrodotoxin (Wikipedia)









Posted: Sunday, March 31, 2013
Last updated: Friday, August 28, 2015