A potent blocker of nicotinic cholinergic receptors (nicotinic acetylcholine receptor, nAChR) found at the neuromuscular junction. At small doses, curare can lead to muscle weakness. At high doses, curare can lead to paralysis of skeletal muscles, which would also result in asphyxiation (and ultimately death) due to paralysis of the diaphragm. Curare was commonly the active agent of poison arrow.

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Leading away from a region or structure of interest.

In the nervous system, efferent fibers (i.e., neurons) transmit information from the central nervous system to peripheral effector organs (i.e., muscles or glands). Therefore, the cells bodies of efferent neurons reside within the central nervous system, whereas their axonal projections exit the central nervous system to make synaptic contact with effector organs in the periphery. Efferent neurons are also referred to as motor neurons.

In the kidneys, the efferent arteriole carries blood away from the glomerular capillaries.

Afferent

Electrophysiology is the study of the electrical properties of biological macromolecules, cells, tissues, and organs. Electrical signals such as voltage and/or current are generally measured. Examples include measuring changes in the membrane voltage of excitable cells (e.g., neurons, muscle cells, and some endocrine cells) during an action potential. The current carrried by ions as they permeate the pore of ion channels can also be measured - both at the single-channel level (single-channel current), as well as the macroscopic current resulting from the activity of a population of channels. As another example, electrical measurements may involve recording voltage changes at the surface of the skin that result from the activity of skeletal muscles (electromyogram, EMG), cardiac myocytes (electrocardiogram, ECG), or neurons in the brain (electroencephalogram, EEG).