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Physiology Test Question
The ion/substrate stoichiometry is 2 Na+ : 1 glucose for the Na+/glucose cotransporter 1 (SGLT1), whereas that for the Na+/glucose cotransporter 2 (SGLT2) is 1 Na+ : 1 glucose. Given this information, which isoform has a higher concentrative capacity (i.e., achieves a higher glucose concentration gradient by accumulating more glucose inside the cell relative to the concentration outside the cell).
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Posted: Monday, January 18, 2016