The main anion (negatively charged ion) of the extracellular fluid.
Cloride (Cl−) plays an important role in several physiological processes such as the action potential of skeletal muscle cells, CO2 transport in blood (via Cl−/bicarbonate exchange across the plasma membrane of red blood cells), and many other processes.
The extracellular concentration of Cl− is about 110 mM. The intracellular concentration of Cl− is about 10 mM.
Posted: Wednesday, February 5, 2014 Last updated: Wednesday, February 5, 2014